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Dimethylamine → Dimethyl-[(1-methyl-1H-indol-3-yl)-o-tolyl-methyl]-amine

HRID 9068
Notes
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Reaction equation

HRID 9068 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3]1.[Cl-].[CH3:12][C:13]1[CH:22]=[CH:21][CH:20]=[CH:19][C:14]=1[CH:15]=[N+:16]([CH3:18])[CH3:17].CC1C=CC=CC=1C=O.CNC>>[CH3:17][N:16]([CH3:18])[CH:15]([C:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:2]([CH3:1])[CH:3]=1)[C:14]1[CH:19]=[CH:20][CH:21]=[CH:22][C:13]=1[CH3:12]
ParticipantsProcedureSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 674DimethylamineHCID 107222-MethylbenzaldehydeHCID 117811-MethylindoleHCID 21985341(2-Methyl-benzylidene)-dimethylammonium chloride

Product 1

HCID 21985352Dimethyl-[(1-methyl-1H-indol-3-yl)-o-tolyl-methyl]-amine

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 1-methyl-1H-indole and (2-methyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-methyl-benzaldehyde and dimethylamine.

On this pageParticipantsProcedureSources & evidenceReaction notes

Sources & evidence

ORD record
ord-9f30dee72cee4b8e950846dc191f7f87
Source dataset
uspto-grants-2006_08
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US07091220B2

Reaction notes

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