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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9069Generated: October 23, 2026

Dimethylamine → [(5-Chloro-1H-indol-3-yl)-o-tolyl-methyl]-dimethyl-amine

https://huagongshe.com/en/reaction/9069

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant2-MethylbenzaldehydeHCID 10722—
Reactant5-ChloroindoleHCID 87110—
Reactant(2-Methyl-benzylidene)-dimethylammonium chlorideHCID 21985341—
Product[(5-Chloro-1H-indol-3-yl)-o-tolyl-methyl]-dimethyl-amineHCID 21985327—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 5-chloro-1H-indole and (2-methyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-methyl-benzaldehyde and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-2d8fffeb348e41d1964f1f9400476c80
Source noteuspto-grants-2006_08