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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9072Generated: October 25, 2026

Dimethylamine → [(5-Chloro-1H-indol-3-yl)-p-tolyl-methyl]-dimethyl-amine

https://huagongshe.com/reaction/9072

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant4-MethylbenzaldehydeHCID 7725—
Reactant5-ChloroindoleHCID 87110—
ReactantN,N-Dimethyl(4-methylphenyl)methaniminium chlorideHCID 13930190—
Product[(5-Chloro-1H-indol-3-yl)-p-tolyl-methyl]-dimethyl-amineHCID 21985334—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 5-chloro-1H-indole and (4-methyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 4-methyl-benzaldehyde and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-d55d366996404928a78cd09f61c25cca
Source noteuspto-grants-2006_08