Reaction equation
Cl.[CH2:2]([NH:6][C:7]([NH:9][C:10]([NH2:12])=[NH:11])=[NH:8])[CH2:3][CH2:4][CH3:5].[OH-].[Na+]>>[CH2:2]([NH:6][C:7]([NH:9][C:10]([NH2:12])=[NH:11])=[NH:8])[CH2:3][CH2:4][CH3:5]Participants
3
Procedure
1-n-Butylbiguanide hydrochloride (product of Wako Pure Chemical Industries) was neutralized with an aqueous solution of sodium hydroxide to give 1-n-butylbiguanide. A 50% methanol solution of this 1-n-butylbiguanide was prepared and use.
Sources & evidence
- ORD record
- ord-c90b75436d20463b882fb9a668b8eb65
- Source dataset
- uspto-grants-2011_09
- Patent number
- US08013080B2
Linked notes
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