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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9077Generated: October 23, 2026

Dimethylamine → [[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-(3-phenoxy-phenyl)-methyl]-dimethyl-amine

https://huagongshe.com/en/reaction/9077

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant3-PhenoxybenzaldehydeHCID 38284—
Reactant2-(4-Fluorophenyl)indoleHCID 136622—
Reactant(3-Phenoxy-benzylidene)-dimethylammonium chlorideHCID 21985375—
Product[[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-(3-phenoxy-phenyl)-methyl]-dimethyl-amineHCID 69374891—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 2-(4-fluoro-phenyl)-1H-indole and (3-phenoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 3-phenoxy-benzaldehyde and dimethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-8282e8e7abbb474d9be6f23017c76a92
Source noteuspto-grants-2006_08