Ammonia → 2-Chloro-N-(2-hydroxy-ethyl)-5-(2-oxo-propyl)-benzenesulfonamide

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](=[O:11])[CH3:10])=[CH:4][C:3]=1[S:12](Cl)(=[O:14])=[O:13].ClC1C=CC(CC(=O)C)=CC=1S(N)(=O)=O.N.[CH2:32]([CH2:34][NH2:35])[OH:33]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](=[O:11])[CH3:10])=[CH:4][C:3]=1[S:12]([NH:35][CH2:34][CH2:32][OH:33])(=[O:14])=[O:13]

Participants

Reactant 4

HCID 222Ammonia

HCID 700Ethanolamine

HCID 578311052-Chloro-5-(2-oxopropyl)benzene-1-sulfonyl chloride

HCID 673923132-Chloro-5-(2-oxo-propyl)-benzenesulfonamide

Product 1

HCID 673909962-Chloro-N-(2-hydroxy-ethyl)-5-(2-oxo-propyl)-benzenesulfonamide

Procedure

This material is prepared from 2-chloro-5-(2-oxopropyl)-benzenesulphonyl chloride (32a) following the same procedure described for the preparation of 2-chloro-5-(2-oxo-propyl)-benzenesulfonamide (33a), replacing ammonia in this procedure with ethanolamine.