5-(2-Morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine → HCID 86761402, compound

Reaction equation

[N:1]1([CH2:7][CH2:8][C:9]2[S:13][C:12]([NH2:14])=[N:11][N:10]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.N1C=CC([NH:20][C:21](N)=[S:22])=N1>>[N:1]1([CH2:7][CH2:8][C:9]2[S:13][C:12]([NH:14][C:21]([NH2:20])=[S:22])=[N:11][N:10]=2)[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1

Participants

Reactant 2

HCID 31640585-(2-Morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine

HCID 178514162HCID 178514162, compound

Product 1

HCID 86761402HCID 86761402, compound

Procedure

The titled compound is prepared from 5-(2-Morpholin-4-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine (54b) following the procedure described for (1H-pyrazol-3-yl)-thiourea (35a)

Sources & evidence

ORD record: ord-67c7fc879dc34e0caa14c7d944968fea
Source dataset: uspto-grants-2011_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08017608B2

Reaction notes

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