2-Chloro-4-phenylquinoline → 9-{4-[4-(4-phenyl-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide
Reaction equation
[Cl:32][c:33]1[n:34][c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]2[c:41](-[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:42]1.[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:30])[F:31]>>[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:24]2[CH2:25][CH2:26][N:27]([c:33]3[n:34][c:35]4[cH:36][cH:37][cH:38][cH:39][c:40]4[c:41](-[c:43]4[cH:44][cH:45][cH:46][cH:47][cH:48]4)[cH:42]3)[CH2:28][CH2:29]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:30])[F:31]Participants
3
Sources & evidence
- ORD record
- ord-5ee71cb0ebf74f178981c0b9b076be24
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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