HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 910233Generated: October 25, 2026
Water → 5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazole
https://huagongshe.com/reaction/910233
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Amino-5-bromobenzene-1-thiol | HCID 1209045 | — |
| Reactant | 4-(5-Oxazolyl)benzaldehyde | HCID 10583346 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazole | HCID 67405287 | 58.8% |
Reaction Steps
2 Amino-5-bromobenzenethiol (102 mg) and 4-(1,3-oxazol-5-yl)benzaldehyde (87 mg) were dissolved in dimethylsulfoxide (1 mL), followed by stirring at 160° C. for 10 minutes. Water (10 mL) was added to the reaction mixture. The precipitated matter was recovered through filtration, and washed with methanol, to thereby yield the title compound (105 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08022075B2 |
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| Source dataset | uspto-grants-2011_09 |
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| ORD ID | ord-0e754375d48d4d6aa7a3d6b803037183 |
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| Source note | uspto-grants-2011_09 |
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