HuagongsheHuagongshe Chemistry Print Report · For research reference only
Styrene → 1-(6-(2(E)-Phenylvinyl)-2-benzothiazolyl)-3-ethylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Styrene | HCID 7501 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,3-Bis(diphenylphosphino)propane | HCID 81219 | — |
| Reactant | 1-(6-Bromo-2-benzothiazolyl)-3-ethylurea | HCID 21985564 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(6-(2(E)-Phenylvinyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985547 | 62% |
Reaction Steps
A mixture of 1-(6-bromo-2-benzothiazolyl)-3-ethylurea, Pd(PPh3)2Cl2, dppp, triethylamine, styrene, and two crystals of BHT in anhydrous DMF was reacted according to the procedure of Example 225 to give the desired compound 0.201 g (62%). LC/MS 324.2 (M+1); LC retention time 2.87 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091227B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-e3c1889fcfaf4fb982b73eceaea5d2bc |
| Source note | uspto-grants-2006_08 |