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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913739Generated: October 26, 2026

Ethane, 1-(2-chloroethoxy)-2-methoxy- → 2-Methyl-1-(2-{[2-(methyloxy)ethyl]oxy}ethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913739

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthane, 1-(2-chloroethoxy)-2-methoxy-HCID 94934—
Reactant2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 53309346—
Product2-Methyl-1-(2-{[2-(methyloxy)ethyl]oxy}ethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67406635—

Reaction Steps

Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 120) and 1-chloro-2-{[2-(methyloxy)ethyl]oxy}ethane: MS (ES) m/z 327 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026262B2
Source datasetuspto-grants-2011_09
ORD IDord-08fdc3ec3dca451c8b0de58fe2c9ff3e
Source noteuspto-grants-2011_09