HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-(6-(3-(3-Tolyl)aminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | m-Tolyl isocyanate | HCID 69303 | — |
| Reactant | 1-(6-(3-Aminophenyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985575 | — |
| Reactant | 1-(6-(3-Phenylaminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985625 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(6-(3-(3-Tolyl)aminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea | HCID 21985513 | 26% |
Reaction Steps
Similar to the synthesis of 1-(6-(3-phenylaminocarbonylaminophenyl)-2-benzothiazolyl)-3-ethylurea, a mixture of 1-(6-(3-aminophenyl)-2-benzothiazolyl)-3-ethylurea, triethylamine, and 3-tolyl isocyanate in toluene was reacted to give the desired compound 0.023 g (26%). LC/MS 446.2 (M+1); LC retention time 3.76 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091227B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-539abe6e916e46699d709602a0ec92f3 |
| Source note | uspto-grants-2006_08 |