Formaldehyde → 2-Hydroxy-3,6-dichloro-5-bromo-benzyl alcohol

HRID 918124

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([Cl:9])=[CH:4][C:3]=1[OH:10].[CH2:11]=[O:12]>>[OH:10][C:3]1[C:2]([Cl:1])=[CH:7][C:6]([Br:8])=[C:5]([Cl:9])[C:4]=1[CH2:11][OH:12]

Participants

Reactant 2

HCID 712Formaldehyde

HCID 160224-Bromo-2,5-dichlorophenol

Product 1

HCID 541223012-Hydroxy-3,6-dichloro-5-bromo-benzyl alcohol

Procedure

2,5-Dichloro-4-bromo-phenol was hydroxymethylated in alkaline aqueous solution with excess formalin at 40°C, using a procedure analogous to that described in U.S. Pat. No. 2,631,169 to produce 2-hydroxy-3,6-dichloro-5-bromo-benzyl alcohol.

Sources & evidence

ORD record: ord-d0248f3533b94061925f3483b64cc08a
Source dataset: uspto-grants-1976_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03969404

Linked notes

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