3-(Trifluoromethyl)aniline → 6-Bromo-N-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918825

Reaction equation

HRID 918825 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6].[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22](OCC)=[O:23])[N:21]=2)[CH:18]=1>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22]([NH:6][C:5]3[CH:7]=[CH:8][CH:9]=[C:3]([C:2]([F:10])([F:11])[F:1])[CH:4]=3)=[O:23])[N:21]=2)[CH:18]=1

Participants

3

Reactant 2

HCID 73753-(Trifluoromethyl)anilineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 897416446-Bromo-N-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridine-2-carboxamide

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using 3-(trifluoromethyl)aniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-080fb57cebc345fb8f236fe886d2139b
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Linked notes

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