Benzenemethanamine, 2,6-dichloro- → 6-Bromo-N-(2,6-dichlorobenzyl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918846

Reaction equation

HRID 918846 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH2:9][NH2:10].[Br:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH:18]=[C:19]([C:21](OCC)=[O:22])[N:20]=2)[CH:17]=1>>[Br:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH:18]=[C:19]([C:21]([NH:10][CH2:9][C:3]3[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][C:4]=3[Cl:8])=[O:22])[N:20]=2)[CH:17]=1

Participants

3

Reactant 2

HCID 485432Benzenemethanamine, 2,6-dichloro-HCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 1181139256-Bromo-N-(2,6-dichlorobenzyl)imidazo[1,2-a]pyridine-2-carboxamide

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (2,6-dichlorophenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-ae50e8212b11479c906701eb95adb23f
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Linked notes

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