Benzenemethanamine, 2,6-dichloro- → 2-bromo-N-(2,6-dichlorobenzyl)imidazo[2,1-b]thiazole-6-carboxamide

HRID 918879

Reaction equation

HRID 918879 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH2:9][NH2:10].[Br:11][C:12]1[S:16][C:15]2=[N:17][C:18]([C:20](O)=[O:21])=[CH:19][N:14]2[CH:13]=1>>[Br:11][C:12]1[S:16][C:15]2=[N:17][C:18]([C:20]([NH:10][CH2:9][C:3]3[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][C:4]=3[Cl:8])=[O:21])=[CH:19][N:14]2[CH:13]=1

Participants

3

Reactant 2

HCID 485432Benzenemethanamine, 2,6-dichloro-HCID 127446152-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid

Product 1

HCID 1181139102-bromo-N-(2,6-dichlorobenzyl)imidazo[2,1-b]thiazole-6-carboxamide

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using (2,6-dichlorophenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Sources & evidence

ORD record
ord-da9d6a91b1da458ba23c0a0bc142033d
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Linked notes

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