4-Bromopyridine-3-carbaldehyde → 1-(4-Bromo-pyridin-3-yl)-4-phenyl-butan-1-ol

HRID 919061Notes

Reaction equation

HRID 919061 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[CH:8]=[O:9].[C:10]1([CH2:16][CH2:17][CH2:18][Mg]Br)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[CH:8]([OH:9])[CH2:18][CH2:17][CH2:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 111167404-Bromopyridine-3-carbaldehydeHCID 178418471HCID 178418471, compound

Product 1

HCID 679577791-(4-Bromo-pyridin-3-yl)-4-phenyl-butan-1-ol

Procedure

Prepared according to the procedure described in Example 5, Step 1, using the following starting materials: 4-bromo-pyridine-3-carbaldehyde and 3-phenyl-propyl magnesium bromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-0f4beb8ecc5d4211a50ffc8465fd5db6
Source dataset
uspto-grants-2016_03
Patent number
US09272990B2

Reaction notes

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