HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Bromo-pyridin-3-yl)-4-phenyl-butan-1-ol → (1-{4'-[3-(1-Hydroxy-4-phenyl-butyl)-pyridin-4-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Bromo-pyridin-3-yl)-4-phenyl-butan-1-ol | HCID 67957779 | — |
| Reactant | {1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester | HCID 67963776 | — |
| Product | (1-{4'-[3-(1-Hydroxy-4-phenyl-butyl)-pyridin-4-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl ester | HCID 67958500 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 2, using the following starting materials: {1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester and 1-(4-bromo-pyridin-3-yl)-4-phenyl-butan-1-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09272990B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-5ff260b35f534ee3bba9bbc146bea59d |
| Source note | uspto-grants-2016_03 |