4-Bromothiophene-3-carboxaldehyde → HCID 67963769, compound

HRID 919073

Reaction equation

HRID 919073 reaction equation
[Br:1][C:2]1[C:3]([CH:7]=[O:8])=[CH:4][S:5][CH:6]=1.[C:9]1([CH2:15][CH2:16][CH2:17][Mg]Br)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[Br:1][C:2]1[C:3]([CH:7]([OH:8])[CH2:17][CH2:16][CH2:15][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:4][S:5][CH:6]=1

Participants

3

Reactant 2

HCID 27642074-Bromothiophene-3-carboxaldehydeHCID 178418471HCID 178418471, compound

Product 1

HCID 67963769HCID 67963769, compound

Procedure

Prepared according to the procedure described in Example 5, Step 1, using the following starting materials: 4-bromo-thiophene-3-carbaldehyde and 3-phenyl-propyl magnesium bromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e5811ddb46884035aee458d77a3e02f9
Source dataset
uspto-grants-2016_03
Patent number
US09272990B2

Linked notes

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