5-Nitrofurfural → HCID 86664232, compound

HRID 919376

Reaction equation

HRID 919376 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[NH:10][N:11]=[CH:12][C:13]1[O:14][C:15]([N+:18]([O-:20])=[O:19])=[CH:16][CH:17]=1.[N+](C1OC(C=O)=CC=1)([O-])=O.N(C1SC2C=C([O:42][C:43]([F:46])([F:45])[F:44])C=CC=2N=1)N>>[F:44][C:43]([F:46])([F:45])[O:42][C:7]1[CH:8]=[CH:9][C:4]2[N:3]=[C:2]([NH:10][N:11]=[CH:12][C:13]3[O:14][C:15]([N+:18]([O-:20])=[O:19])=[CH:16][CH:17]=3)[S:1][C:5]=2[CH:6]=1

Participants

4

Reactant 3

HCID 127745-NitrofurfuralHCID 28566715-Nitro-2-furaldehyde 2-(1,3-benzothiazole-2-yl)hydrazoneHCID 104221582-Hydrazinyl-6-(trifluoromethoxy)-1,3-benzothiazole

Product 1

HCID 86664232HCID 86664232, compound

Procedure

The compound 3i was prepared according procedure described for 3a by employing 5-nitrofuran aldehyde (141 mg, 1 mmol) and 2-hydrazino-6-trifluoromethoxy-benzothiazole (249 mg, 1 mmol) at 70° C. for 2 h (yield 298 mg, 80%).

Workup

  1. customat 70° C.
  2. customfor 2 h

Sources & evidence

ORD record
ord-fff655b9fc1b4e0cb0920dc10e260265
Source dataset
uspto-grants-2016_03
Patent number
US09273039B2

Linked notes

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