Pyrimidin-5-ol → 5-Formyl-2-(pyrimidin-5-yloxy)benzonitrile

HRID 920334

Reaction equation

HRID 920334 reaction equation
F[C:2]1[CH:9]=[CH:8][C:7]([CH:10]=[O:11])=[CH:6][C:3]=1[C:4]#[N:5].[N:12]1[CH:17]=[C:16]([OH:18])[CH:15]=[N:14][CH:13]=1>>[CH:10]([C:7]1[CH:8]=[CH:9][C:2]([O:18][C:16]2[CH:17]=[N:12][CH:13]=[N:14][CH:15]=2)=[C:3]([CH:6]=1)[C:4]#[N:5])=[O:11]

Participants

3

Reactant 2

HCID 565855Pyrimidin-5-olHCID 27695822-Fluoro-5-formylbenzonitrile

Product 1

HCID 866763815-Formyl-2-(pyrimidin-5-yloxy)benzonitrile

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from 2-fluoro-5-formylbenzonitrile and pyrimidin-5-ol.

Sources & evidence

ORD record
ord-12dcff702e7e4291ab780ac3f6d76a74
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Linked notes

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