Methyl 3-(4-hydroxyphenyl)-3-(1,2-oxazol-3-yl)propanoate → 3-[4-[[4-[(2Z)-2-methoxyimino-2-phenylethoxy]phenyl]methoxy]phenyl]-3-(1,2-oxazol-3-yl)propanoic acid
Reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:14]2[CH:18]=[CH:17][O:16][N:15]=2)[CH2:9][C:10]([O:12]C)=[O:11])=[CH:4][CH:3]=1.[CH3:19][O:20]/[N:21]=[C:22](/[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)\[CH2:23][O:24][C:25]1[CH:30]=[CH:29][C:28]([CH2:31]O)=[CH:27][CH:26]=1>>[CH3:19][O:20]/[N:21]=[C:22](/[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)\[CH2:23][O:24][C:25]1[CH:30]=[CH:29][C:28]([CH2:31][O:1][C:2]2[CH:7]=[CH:6][C:5]([CH:8]([C:14]3[CH:18]=[CH:17][O:16][N:15]=3)[CH2:9][C:10]([OH:12])=[O:11])=[CH:4][CH:3]=2)=[CH:27][CH:26]=1Participants
3
Procedure
Compound 17 was prepared by using methyl 3-(4-hydroxyphenyl)-3-(1,2-oxazol-3-yl)propanoate and (4-{[(2Z)-2-(Methoxyimino)-2-phenylethyl]oxy}phenyl) methanol by following the procedure described in Scheme 11.
Sources & evidence
- ORD record
- ord-e45f8fdfcaa846dd80e009b61ff6b5ab