Acetic Anhydride → 2,3-Dimethylsuccinic anhydride
Reaction equation
[CH3:1][CH:2]([CH:6]([CH3:10])[C:7]([OH:9])=[O:8])[C:3](O)=[O:4].CC(OC(C)=O)=O>>[CH3:1][CH:2]1[CH:6]([CH3:10])[C:7](=[O:9])[O:8][C:3]1=[O:4]Participants
3
Procedure
2,3-Dimethyl succinic anhydride was prepared as described in Sutton, et al. OPPI 24 (1992) 39. Briefly, 7.1 g 2,3-dimethyl succinic acid and 6.9 ml acetanhydride were slowly heated up to 50° C. for 3 hours. Then acetanhydride was removed by distillation. The product was recrystallized from ethanol abs. and characterized by the melting point.
Workup
- customThen acetanhydride was removed by distillation
- customThe product was recrystallized from ethanol abs
Sources & evidence
- ORD record
- ord-5403135eb5204daea138e61c612c7f0d
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09283186B2
Reaction notes
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