Ethyl 2-(3-vinylphenyl)acetate → Ethyl 2-(3-ethylphenyl)acetate
Reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:6]=[CH:7][CH:8]=1)=[CH2:2]>C(O)C.[Pd]>[CH2:1]([C:3]1[CH:4]=[C:5]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:6]=[CH:7][CH:8]=1)[CH3:2]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 30 °C
Procedure
To a solution of ethyl 2-(3-vinylphenyl)acetate (640 mg, 3.6 mmol) in ethanol (10 mL) was added 10% of Pd/C (100 mg) and stirred at 30° C. under hydrogen atmosphere (15 psi) for 7 hours. Then the solution was filtered and the solvent was removed in vacuo (500 mg, yield 77%).
Workup
- filtrationThen the solution was filtered
- customthe solvent was removed in vacuo (500 mg, yield 77%)
Sources & evidence
- ORD record
- ord-74620268fa014d59beb406a5dae1a703
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09283229B2
Reaction notes
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