HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorodiisopropylphosphine → N1-(2-isopropyl-6-methylphenyl)-N2-(diisopropyl-phosphino)-4-methylbenzamidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorodiisopropylphosphine | HCID 538967 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Reactant | HCID 178425631 | HCID 178425631 | — |
| Product | N1-(2-isopropyl-6-methylphenyl)-N2-(diisopropyl-phosphino)-4-methylbenzamidine | HCID 178425661 | — |
Reaction Steps
Procedure as described for NP Amidine I using the following amounts: 1.33 g of N1-(2-isopropyl-6-methylphenyl)-4-methylbenzamidine (Amidine V, 5.0 mmol), 2.50 mL of 2.0 M butyllithium (5.0 mmol), 0.80 mL chlorodiisopropylphosphine (5.0 mmol). After filtration to remove lithium chloride and removal of solvent, a yellow semi-solid was isolated (1.86 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09283555B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-0dc94fc71bc24b18b415f2c8fc3d938c |
| Source note | uspto-grants-2016_03 |