1,4-Dioxane → (2-{2-[3-(4-Methylpiperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophen-6-ylmethyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][c:9]1[cH:10][cH:11][c:12]2[c:13]([s:14][c:15](-[c:17]3[n:18][c:19]([Cl:23])[n:20][cH:21][cH:22]3)[cH:16]2)[cH:24]1)=[O:25].[NH2:26][CH2:27][CH2:28][CH2:29][N:30]1[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]1.[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][c:9]1[cH:10][cH:11][c:12]2[c:13]([s:14][c:15](-[c:17]3[n:18][c:19]([NH:26][CH2:27][CH2:28][CH2:29][N:30]4[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]4)[n:20][cH:21][cH:22]3)[cH:16]2)[cH:24]1)=[O:25]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-162342f673d844ebb802b35abf39a4ab