Methanol → N-[2-[[1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-fluoro-5-(trifluoromethyl)benzamide

HRID 92673

Reaction equation

HRID 92673 reaction equation
[CH3:15][c:16]1[n:17][o:18][c:19]([CH3:32])[c:20]1[CH2:21][N:22]1[CH2:23][CH:24]([NH:27][C:28]([CH2:29][NH2:30])=[O:31])[CH2:25][CH2:26]1.[CH3:33][OH:34].[CH:35]([Cl:36])([Cl:37])[Cl:38].[Cl:39][CH2:40][Cl:41].[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[Cl:7])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1>>[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:30][CH2:29][C:28]([NH:27][CH:24]2[CH2:23][N:22]([CH2:21][c:20]3[c:16]([CH3:15])[n:17][o:18][c:19]3[CH3:32])[CH2:26][CH2:25]2)=[O:31])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1

Participants

6

Reactant 5

HCID 887MethanolHCID 6212ChloroformHCID 6344DichloromethaneHCID 5193643-Fluoro-5-(trifluoromethyl)benzoyl chlorideHCID 184261742-amino-N-[1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]pyrrolidin-3-yl]acetamide

Product 1

HCID 18426151N-[2-[[1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-fluoro-5-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-876b9db09aec41ec867fb930074670b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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