methyl (1aRS,7bSR)-5-[N-(2-bromo-4-fluorobenzenesulfonyl)-N-(methoxycarbonyl)amino]-1,1a,2,7b-tetrahydrocyclopropa-[c]chromene-4-carboxylate → Methyl (1aRS,7bSR)-5-{N-[methoxycarbonyl]-N-[2-((Z)-4-hydroxybut-1-enyl)-4-fluorobenzenesulfonyl]amino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylate

Reaction equation

[CH3:1][O:2][C:3]([N:5]([C:20]1[C:29]([C:30]([O:32][CH3:33])=[O:31])=[C:28]2[C:23]([CH:24]3[CH2:34][CH:25]3[CH2:26][O:27]2)=[CH:22][CH:21]=1)[S:6]([C:9]1[CH:14]=[CH:13][C:12]([F:15])=[CH:11][C:10]=1/[CH:16]=[CH:17]\[CH2:18]O)(=[O:8])=[O:7])=[O:4].BrC1C=C(F)C=CC=1S(N(C1C(C(OC)=O)=C2C(C3CC3CO2)=CC=1)[C:47](OC)=[O:48])(=O)=O>>[CH3:1][O:2][C:3]([N:5]([C:20]1[C:29]([C:30]([O:32][CH3:33])=[O:31])=[C:28]2[C:23]([CH:24]3[CH2:34][CH:25]3[CH2:26][O:27]2)=[CH:22][CH:21]=1)[S:6]([C:9]1[CH:14]=[CH:13][C:12]([F:15])=[CH:11][C:10]=1/[CH:16]=[CH:17]\[CH2:18][CH2:47][OH:48])(=[O:7])=[O:8])=[O:4]