Dichloromethane → HCID 58081285, compound

Reaction equation

[O:1]=[S:2]1(=[O:13])[CH2:6][CH2:5][C:4]2[CH:7]=[C:8]([CH2:11][OH:12])[CH:9]=[CH:10][C:3]1=2.C(Cl)Cl>>[O:1]=[S:2]1(=[O:13])[CH2:6][CH2:5][C:4]2[CH:7]=[C:8]([CH2:11][O:12][S:2]([CH3:3])(=[O:13])=[O:1])[CH:9]=[CH:10][C:3]1=2

Participants

Reactant 2

HCID 6344Dichloromethane

HCID 17966965HCID 17966965, compound

Product 1

HCID 58081285HCID 58081285, compound

Procedure

To a solution of (1,1-Dioxo-2,3-dihydro-1H-1lambda*6*-benzo[b]thiophen-5-yl)-methanol (crude, 160 mg, 0.64 mmol) and triethylamne (180 ul, 1.29 mmol) in DCM (7 ml) Methanesulfonylchloride (60 ul, 0.77 mmol) was added at rt. The reaction mixture was stirred at it for 3 hours.

Sources & evidence

ORD record: ord-d527cf76fa4b4b75a7248d1d8db795d9
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09290485B2

Reaction notes

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