4-Nitrobenzoic Acid → N-methoxy-N-methyl-4-nitrobenzamide

HRID 928745

Reaction equation

HRID 928745 reaction equation
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8](O)=[O:9])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:13][O:14][N:15](C)[C:16](C1SC=NC=1)=O>>[CH3:13][O:14][N:15]([CH3:16])[C:8](=[O:9])[C:7]1[CH:11]=[CH:12][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 61084-Nitrobenzoic AcidHCID 25307138N-Methoxy-N-methyl-1,3-thiazole-5-carboxamide

Product 1

HCID 2991007N-methoxy-N-methyl-4-nitrobenzamide

Procedure

The title compound was prepared by substituting thiazole-5-carboxylic acid with 4-nitrobenzoic acid then following the procedure described for the preparation of N-methoxy-N-methylthiazole-5-carboxamide (Intermediate 11: step a).

Sources & evidence

ORD record
ord-52d30d7cc6d040a1bb28526113912dd7
Source dataset
uspto-grants-2016_03
Patent number
US09290476B2

Linked notes

Loading…