1-Indanone, 4-bromo- → 4-(4-Bromo-indan-1-ylmethyl)-1,3-dihydro-imidazole-2-thione

HRID 9289

Reaction equation

HRID 9289 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][C:6]2=O.BrC1C=CC=C2C=1C[CH:16]([C:22]1[NH:23][C:24](=[S:27])[NH:25][CH:26]=1)C2>>[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][CH:6]2[CH2:16][C:22]1[NH:23][C:24](=[S:27])[NH:25][CH:26]=1

Participants

3

Reactant 2

HCID 987131-Indanone, 4-bromo-HCID 21986168HCID 21986168, compound

Product 1

HCID 219860654-(4-Bromo-indan-1-ylmethyl)-1,3-dihydro-imidazole-2-thione

Procedure

Use of 4-bromoindanone (obtained by the procedures in Example NINETEEN-1 (Compound 149) in Method TWENTYFOUR produced 4-(4-bromo-indan-1-ylmethyl)-1,3-dihydro-imidazole-2-thione (Compound 167).

Sources & evidence

ORD record
ord-3bd5b34b9668455190055c5e0f263011
Source dataset
uspto-grants-2006_08
Patent number
US07091232B2

Linked notes

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