(5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(dicyclopropylmethyl)-5,6-dihydropyridin-2(1H)-one → (5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(dicyclopropylmethyl)piperidin-2-one
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C@@H:8]2[C@@H:13]([C:14]3[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=3)[N:12]([CH:21]([CH:25]3[CH2:27][CH2:26]3)[CH:22]3[CH2:24][CH2:23]3)[C:11](=[O:28])[CH:10]=[CH:9]2)[CH:5]=[CH:6][CH:7]=1.[H][H]>C(Cl)Cl.C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.C1CC=CCCC=C1.C1C=CN=CC=1.F[P-](F)(F)(F)(F)F.[Ir]>[Cl:1][C:2]1[CH:3]=[C:4]([C@@H:8]2[C@@H:13]([C:14]3[CH:15]=[CH:16][C:17]([Cl:20])=[CH:18][CH:19]=3)[N:12]([CH:21]([CH:22]3[CH2:24][CH2:23]3)[CH:25]3[CH2:27][CH2:26]3)[C:11](=[O:28])[CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1Participants
5
