6-(Hydroxymethyl)pyridine-3-boronic acid → 1-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)-8-(6-hydroxymethyl-pyridin-3-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

HRID 932387

Reaction equation

HRID 932387 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:24])[c:13](=[O:23])[n:14]3-[c:15]1[c:16]([CH3:22])[n:17][n:18]([CH2:20][CH3:21])[cH:19]1.[OH:25][CH2:26][c:27]1[cH:28][cH:29][c:30]([B:33]([OH:34])[OH:35])[cH:31][n:32]1>>[c:2]1(-[c:30]2[cH:29][cH:28][c:27]([CH2:26][OH:25])[n:32][cH:31]2)[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:24])[c:13](=[O:23])[n:14]3-[c:15]1[c:16]([CH3:22])[n:17][n:18]([CH2:20][CH3:21])[cH:19]1

Participants

3

Reactant 2

HCID 441182556-(Hydroxymethyl)pyridine-3-boronic acidHCID 596196758-bromo-1-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

Product 1

HCID 498353111-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)-8-(6-hydroxymethyl-pyridin-3-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

Sources & evidence

ORD record
ord-87a3238f22a34546bd2001f995b55d24
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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