Water → 8-Bromo-2-(cyclohexyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

HRID 93395

Reaction equation

HRID 93395 reaction equation
[Br:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[CH:33]([Cl:34])([Cl:35])[Cl:36].[CH:9]1([O:15][c:16]2[n:17][c:18]([NH2:31])[c:19]3[n:20][cH:21][n:22]([CH:25]4[O:26][CH2:27][CH2:28][CH2:29][CH2:30]4)[c:23]3[n:24]2)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]1.[OH2:32]>>[Br:1][c:21]1[n:20][c:19]2[c:18]([NH2:31])[n:17][c:16]([O:15][CH:9]3[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]3)[n:24][c:23]2[n:22]1[CH:25]1[O:26][CH2:27][CH2:28][CH2:29][CH2:30]1

Participants

5

Reactant 4

HCID 962WaterHCID 6212ChloroformHCID 67184N-bromobutanimideHCID 592525752-(Cyclohexyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

Product 1

HCID 592526578-Bromo-2-(cyclohexyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

Sources & evidence

ORD record
ord-ade34211b9634318a46aa0be8b377623
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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