(Pyridin-4-yl)boronic acid → N-cyclopentyl-3-[2-(cyclopentylamino)-4-pyrimidinyl]-2-[3-(4-pyridinyl)phenyl]pyrazolo[1,5-a]pyridin-7-amine

Reaction equation

[Br:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][c:15]3[NH:16][CH:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[c:22]2-[c:23]2[n:24][c:25]([NH:29][CH:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)[n:26][cH:27][cH:28]2)[cH:5][cH:6][cH:7]1.[n:35]1[cH:36][cH:37][c:38]([B:41]([OH:42])[OH:43])[cH:39][cH:40]1>>[c:2]1(-[c:38]2[cH:37][cH:36][n:35][cH:40][cH:39]2)[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][c:15]3[NH:16][CH:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[c:22]2-[c:23]2[n:24][c:25]([NH:29][CH:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)[n:26][cH:27][cH:28]2)[cH:5][cH:6][cH:7]1

Participants

Reactant 2

HCID 2734379(Pyridin-4-yl)boronic acid

HCID 10142612HCID 10142612, compound

Product 1

HCID 10164744N-cyclopentyl-3-[2-(cyclopentylamino)-4-pyrimidinyl]-2-[3-(4-pyridinyl)phenyl]pyrazolo[1,5-a]pyridin-7-amine

Sources & evidence

ORD record: ord-ba6e36d304da4107b592a147873570fb
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…