Methanol → 7-bromo-5-fluoro-3,4-dihydro-2H-naphthalen-1-ol
Reaction equation
[BH4-:14].[Br:1][c:2]1[cH:3][c:4]([F:13])[c:5]2[c:10]([cH:11]1)[C:9](=[O:12])[CH2:8][CH2:7][CH2:6]2.[CH3:17][OH:18].[Cl:19][CH2:20][Cl:21].[Na+:15].[OH2:16]>>[Br:1][c:2]1[cH:3][c:4]([F:13])[c:5]2[c:10]([cH:11]1)[CH:9]([OH:12])[CH2:8][CH2:7][CH2:6]2Participants
7
Sources & evidence
- ORD record
- ord-e7a69f39429442a3921f94ad36489a67
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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