Dimethylamine → 8-(2-Dimethylamino-pyridine-3-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[CH3:33][NH:34][CH3:35].[Cl:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[N:11]1[CH2:12][CH2:13][C:14]2([CH2:15][CH2:16][N:17]([c:20]3[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]3)[C:18]2=[O:19])[CH2:31][CH2:32]1>>[c:2]1([N:34]([CH3:33])[CH3:35])[n:3][cH:4][cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[N:11]1[CH2:12][CH2:13][C:14]2([CH2:15][CH2:16][N:17]([c:20]3[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]3)[C:18]2=[O:19])[CH2:31][CH2:32]1Participants
3
Sources & evidence
- ORD record
- ord-3aa66f997a51449099b9c225d855a919
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…