Toluene → 4-Chloro-5-fluoro-2-methyl-quinolin-8-ol
Reaction equation
[B:16]([Br:17])([Br:18])[Br:19].[CH3:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[Cl:1][c:2]1[cH:3][c:4]([CH3:15])[n:5][c:6]2[c:7]([O:13][CH3:14])[cH:8][cH:9][c:10]([F:12])[c:11]12.[Cl:27][CH2:28][Cl:29]>>[Cl:1][c:2]1[cH:3][c:4]([CH3:15])[n:5][c:6]2[c:7]([OH:13])[cH:8][cH:9][c:10]([F:12])[c:11]12Participants
5
Sources & evidence
- ORD record
- ord-1a6403b5298540cca27c2cf0fe209358
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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