Acetonitrile → 3-Iodo-7-(4-methanesulfonyl-phenyl)-imidazo[1,2-a]pyridine

Reaction equation

[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]3[n:14]([cH:15][cH:16]2)[cH:17][cH:18][n:19]3)[cH:9][cH:10]1.[CH3:28][C:29]#[N:30].[O:20]=[C:21]1[N:22]([I:27])[C:23](=[O:24])[CH2:25][CH2:26]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]3[n:14]([cH:15][cH:16]2)[c:17]([I:27])[cH:18][n:19]3)[cH:9][cH:10]1

Participants

Reactant 3

HCID 6342Acetonitrile

HCID 120273N-Iodosuccinimide

HCID 68543695Imidazo[1,2-a]pyridine,7-[4-(methylsulfonyl)phenyl]-

Product 1

HCID 685436593-Iodo-7-(4-methanesulfonyl-phenyl)-imidazo[1,2-a]pyridine

Sources & evidence

ORD record: ord-179c12b06d5c4e72874bf3edc3a41762
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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