Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin]-2'-one → 3-(5-Pyridin-2-ylthiophen-3-yl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one

HRID 943464

Reaction equation

HRID 943464 reaction equation
[Br:14][c:15]1[cH:16][c:17](-[c:20]2[n:21][cH:22][cH:23][cH:24][cH:25]2)[s:18][cH:19]1.[O:1]1[C:2](=[O:13])[NH:3][CH2:4][C:5]12[CH2:6][N:7]1[CH2:8][CH2:9][CH:10]2[CH2:11][CH2:12]1>>[O:1]1[C:2](=[O:13])[N:3]([c:15]2[cH:16][c:17](-[c:20]3[n:21][cH:22][cH:23][cH:24][cH:25]3)[s:18][cH:19]2)[CH2:4][C:5]12[CH2:6][N:7]1[CH2:8][CH2:9][CH:10]2[CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 9852730Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin]-2'-oneHCID 142923562-(4-Bromothiophen-2-yl)pyridine

Product 1

HCID 690599343-(5-Pyridin-2-ylthiophen-3-yl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one

Sources & evidence

ORD record
ord-f27917f40a7e4c1ab1db1a4586579fb3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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