Acetone → Ethyl 3-phenyl-3-[6-(3-hydroxypropoxy)indol-3-yl]propionate

HRID 944761

Reaction equation

HRID 944761 reaction equation
[Br:24][CH2:25][CH2:26][CH2:27][OH:28].[C:29](=[O:30])([O-:31])[O-:32].[CH3:35][C:36](=[O:37])[CH3:38].[K+:33].[K+:34].[c:1]1([CH:7]([CH2:8][C:9](=[O:10])[O:11][CH2:12][CH3:13])[c:14]2[cH:15][nH:16][c:17]3[cH:18][c:19]([OH:23])[cH:20][cH:21][c:22]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH2:8][C:9](=[O:10])[O:11][CH2:12][CH3:13])[c:14]2[cH:15][nH:16][c:17]3[cH:18][c:19]([O:23][CH2:25][CH2:26][CH2:27][OH:28])[cH:20][cH:21][c:22]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 123083-Bromo-1-propanolHCID 19660Carbonate IonHCID 15549281Ethyl 3-phenyl-3-(6-hydroxyindol-3-yl)propionate

Product 1

HCID 15549282Ethyl 3-phenyl-3-[6-(3-hydroxypropoxy)indol-3-yl]propionate

Sources & evidence

ORD record
ord-5bc2d4151bfb4955a23972aba735d350
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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