Water → N-(4-amino-5-cyano-6-isopropoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

HRID 944856

Reaction equation

HRID 944856 reaction equation
[CH3:15][O:16][c:17]1[c:18]([CH2:25][C:26](=[O:27])[Cl:28])[cH:19][c:20]([O:23][CH3:24])[cH:21][cH:22]1.[Cl:36][CH2:37][Cl:38].[NH2:1][c:2]1[cH:3][c:4]([NH2:14])[n:5][c:6]([O:10][CH:11]([CH3:12])[CH3:13])[c:7]1[C:8]#[N:9].[OH2:29].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[NH2:1][c:2]1[cH:3][c:4]([NH:14][C:26]([CH2:25][c:18]2[c:17]([O:16][CH3:15])[cH:22][cH:21][c:20]([O:23][CH3:24])[cH:19]2)=[O:27])[n:5][c:6]([O:10][CH:11]([CH3:12])[CH3:13])[c:7]1[C:8]#[N:9]

Participants

6

Reactant 5

HCID 962WaterHCID 1049PyridineHCID 6344DichloromethaneHCID 596088(2,5-Dimethoxyphenyl)acetyl chlorideHCID 11550144HCID 11550144, compound

Product 1

HCID 11610382N-(4-amino-5-cyano-6-isopropoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

Sources & evidence

ORD record
ord-2ccb8f9e54804f7f9b616a1ff04de27e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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