4-Iodoanisole → (2-Amino-6-chloro-pyridin-3-yl)-(4-methoxy-phenyl)-methanone

HRID 945331

Reaction equation

HRID 945331 reaction equation
[CH3:15][O:16][c:17]1[cH:18][cH:19][c:20]([Li:23])[cH:21][cH:22]1.[I:24][c:25]1[cH:26][cH:27][c:28]([O:29][CH3:30])[cH:31][cH:32]1.[NH2:1][c:2]1[c:3]([C:4](=[O:5])[N:6]([O:7][CH3:8])[CH3:9])[cH:10][cH:11][c:12]([Cl:14])[n:13]1>>[NH2:1][c:2]1[c:3]([C:4](=[O:5])[c:20]2[cH:19][cH:18][c:17]([O:16][CH3:15])[cH:22][cH:21]2)[cH:10][cH:11][c:12]([Cl:14])[n:13]1

Participants

4

Reactant 3

HCID 696764-IodoanisoleHCID 585908242-Amino-6-chloro-N-methoxy-N-methyl-nicotinamideHCID 178506735HCID 178506735, compound

Product 1

HCID 58590836(2-Amino-6-chloro-pyridin-3-yl)-(4-methoxy-phenyl)-methanone

Sources & evidence

ORD record
ord-31f69543358746ba8aa7fdf1ea260eb8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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