Pyridine → 2-Methyl-3-hydroxy-4-acetyl-5-vinylpyridine

Reaction equation

[CH2:24]([Cl:25])[Cl:26].[CH3:11][c:12]1[n:13][cH:14][c:15]([CH:22]=[CH2:23])[c:16]([CH:19]([CH3:20])[OH:21])[c:17]1[OH:18].[O:7]=[Cr:8](=[O:9])=[O:10].[cH:1]1[cH:2][cH:3][n:4][cH:5][cH:6]1>>[CH3:11][c:12]1[n:13][cH:14][c:15]([CH:22]=[CH2:23])[c:16]([C:19]([CH3:20])=[O:21])[c:17]1[OH:18]

Participants

Reactant 4

HCID 1049Pyridine

HCID 6344Dichloromethane

HCID 14915Chromium Trioxide

HCID 202639212-Methyl-3-hydroxy-4-(1-hydroxyethyl)-5-vinylpyridine

Product 1

HCID 202640462-Methyl-3-hydroxy-4-acetyl-5-vinylpyridine

Sources & evidence

ORD record: ord-73698fc185da4b9893711a60c0aa5f18
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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