Methanol → trans-4-(4-Tert-butoxycarbonyl-2-oxo-piperazin-1-YL)cyclohexanecarboxylic acid

Reaction equation

[CH3:1][O:2][C:3](=[O:4])[CH:5]1[CH2:6][CH2:7][CH:8]([N:11]2[C:12](=[O:24])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[CH2:9][CH2:10]1.[CH3:27][OH:28].[Na+:26].[OH-:25]>>[O:2]=[C:3]([OH:4])[CH:5]1[CH2:6][CH2:7][CH:8]([N:11]2[C:12](=[O:24])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[CH2:9][CH2:10]1