Ethylenediamine → N-(2-amino-4-fluorophenyl)-6-(2-aminoethylamino)nicotinamide
Reaction equation
[NH2:19][CH2:20][CH2:21][NH2:22].[NH2:1][c:2]1[c:3]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([Cl:17])[cH:15][cH:16]2)=[O:18])[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[NH2:1][c:2]1[c:3]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([NH:19][CH2:20][CH2:21][NH2:22])[cH:15][cH:16]2)=[O:18])[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-ebe97695ce7a423786fee625381a6377
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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