2-(2,5-Dichloro-pyrimidin-4-ylamino)-N,N-dimethyl-benzenesulfonamide → 2-(5-Chloro-2-{8-methoxy-3-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ylamino}-pyrimidin-4-ylamino)-N,N-dimethyl-benzenesulfonamide

Reaction equation

[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[N:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1.[NH2:22][c:23]1[cH:24][c:25]2[c:26]([cH:42][c:43]1[O:44][CH3:45])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]1[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]1)[CH2:30][CH2:31]2>>[c:2]1([NH:22][c:23]2[cH:24][c:25]3[c:26]([cH:42][c:43]2[O:44][CH3:45])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]2[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]2)[CH2:30][CH2:31]3)[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[N:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1