Pyridine → 8-Chloro-1-cyclopropyl-6-fluoro-7-[4-(2-hydroxyethyl)-1,4-diazepan-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Reaction equation
[Cl:1][c:2]1[c:3]([F:20])[c:4]([F:19])[cH:5][c:6]2[c:7](=[O:18])[c:8]([C:15](=[O:16])[OH:17])[cH:9][n:10]([CH:12]3[CH2:13][CH2:14]3)[c:11]12.[N:21]1([CH2:28][CH2:29][OH:30])[CH2:22][CH2:23][NH:24][CH2:25][CH2:26][CH2:27]1.[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[Cl:1][c:2]1[c:3]([N:24]2[CH2:23][CH2:22][N:21]([CH2:28][CH2:29][OH:30])[CH2:27][CH2:26][CH2:25]2)[c:4]([F:19])[cH:5][c:6]2[c:7](=[O:18])[c:8]([C:15](=[O:16])[OH:17])[cH:9][n:10]([CH:12]3[CH2:13][CH2:14]3)[c:11]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-4392379571a241d78217847a40c4b6bd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D