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Sodium Ion → ethyl (RS)-[3-oxo-2-(2,2,2-trifluoroethyl)-6-trifluoromethyl-2,3-dihydro-1H-isoindol-1-yl]acetate

HRID 949076
Notes
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Reaction equation

HRID 949076 reaction equation
[CH2:3]([CH3:4])[O:5][C:6]([CH2:7][P:8]([O:9][CH2:10][CH3:11])([O:12][CH2:13][CH3:14])=[O:15])=[O:16].[H-:2].[Na+:1].[OH:17][CH:18]1[N:19]([CH2:32][C:33]([F:34])([F:35])[F:36])[C:20](=[O:31])[c:21]2[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][c:26]21>>[CH2:3]([CH3:4])[O:5][C:6]([CH2:7][CH:18]1[N:19]([CH2:32][C:33]([F:34])([F:35])[F:36])[C:20](=[O:31])[c:21]2[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][c:26]21)=[O:16]
ParticipantsSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 923Sodium IonHCID 13345Triethyl phosphonoacetateHCID 166653HydrideHCID 17966419HCID 17966419, compound

Product 1

HCID 57678949ethyl (RS)-[3-oxo-2-(2,2,2-trifluoroethyl)-6-trifluoromethyl-2,3-dihydro-1H-isoindol-1-yl]acetate

Sources & evidence

ORD record
ord-61228f1530d44623bb41e0ee49a0fb22
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes