3-(Difluoromethoxy)benzenesulfonyl chloride → 3-[1-(3-Difluoromethoxy-benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-azetidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([c:12]2[cH:13][c:14]3[c:15]([n:16][cH:17]2)[nH:18][cH:19][cH:20]3)[CH2:11]1.[F:21][CH:22]([O:23][c:24]1[cH:25][c:26]([S:30](=[O:31])(=[O:32])[Cl:33])[cH:27][cH:28][cH:29]1)[F:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([c:12]2[cH:13][c:14]3[c:15]([n:16][cH:17]2)[n:18]([S:30]([c:26]2[cH:25][c:24]([O:23][CH:22]([F:21])[F:34])[cH:29][cH:28][cH:27]2)(=[O:31])=[O:32])[cH:19][cH:20]3)[CH2:11]1Participants
3
Sources & evidence
- ORD record
- ord-9b863cc0ca98485c887d60b9ef34a4f3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…